Subtract
“Subtract” by Derek Sivers (@sivers), my favorite musician-programmer-philosopher. For more Derek wisdom and hilarity, be sure to check out this and this.— Tim Ferriss
Everything Tim Ferriss has recommended in 5-Bullet Friday — 2,095 books, articles, quotes, films, products and more, gathered from 480 issues since 2015. Browse by category, sort by what the community values or how often Tim has returned to it, and spend your 25 votes on what matters most to you. Each item's note is quoted from Tim's own words in the newsletter.
“Subtract” by Derek Sivers (@sivers), my favorite musician-programmer-philosopher. For more Derek wisdom and hilarity, be sure to check out this and this.— Tim Ferriss
“A Pickpocket’s Tale: The spectacular thefts of Apollo Robbins” by Adam Green (The New Yorker). This was sent to me by Jeffrey Zurofsky (“JZ” from The 4-Hour Chef). Here’s one paragraph to give you a taste: When Robbins hits his stride, it starts to seem as if the only possible explanation is an ability to start and stop time. At the Rio, a man’s cell phone disappeared from his jacket and was replaced by a piece of fried chicken; the cigarettes from a pack in one man’s breast pocket materialized loose in the side pocket of another; a woman’s engagement ring vanished and reappeared attached to — Tim Ferriss
“How do you ask good questions?” by Tyler Cowen. Tyler always impresses me. His tips here will make you a better thinker and a better conversationalist. For more Tyler, check out our long-form discussion here.— Tim Ferriss
“The Four Buddhist Mantras for Turning Fear into Love” by Maria Popova. Thanks to JZ for the recommendation.— Tim Ferriss
“The Most Important Question of Your Life” by Mark Manson. I could reread this once a week and still benefit. Excellent reminders all around. “So you wanna de-bog yourself” by Adam Mastroianni. I only found Adam in July of 2024, but his writing is some of the most hilarious—and helpful—I’ve seen in a long time. Really worth the read. Deep bow to Crazy B for sending this to me. “A message for the New Year” from Brandon Stanton, creator of Humans of New York. This relates to something he and I have texted about often: attention. How should you think about protecting your own attention in 2026? I— Tim Ferriss
“A message for the New Year” from Brandon Stanton, creator of Humans of New York. This relates to something he and I have texted about often: attention. How should you think about protecting your own attention in 2025? If you don’t have attention, the time and money you have matter little. Attention is the mother resource. Brandon’s post was first written earlier this year, but it’s more relevant every day. Coach Christopher Sommer’s email to me. Coach Sommer is a former US National Team gymnastics coach and the creator of GymnasticBodies. “Why You Should Seek More Awe in the New Year” by Ashl— Tim Ferriss
“How To Be Successful,” 13 lessons on achieving outlier success written by Sam Altman (@sama), CEO of OpenAI. Here is one of the many paragraphs I highlighted for myself: “It’s useful to focus on adding another zero to whatever you define as your success metric—money, status, impact on the world, or whatever. I am willing to take as much time as needed between projects to find my next thing. But I always want it to be a project that, if successful, will make the rest of my career look like a footnote.” Here is another: “I believe that it’s easier to do a hard startup than an easy startup. Peop— Tim Ferriss
“Taming the Mammoth: Why You Should Stop Caring What Other People Think.” This remains one of the most empowering articles I’ve read in recent years. It’s hilarious and amazing. For double trouble, pair it with my interview with the author, Tim Urban (@waitbutwhy).— Tim Ferriss
“The DIY Scientist, the Olympian, and the Mutated Gene” by David Epstein (@DavidEpstein). This is a fantastic read, especially for science nerds, about how a layperson can spot breakthrough ideas that the experts miss.— Tim Ferriss
“Man of Extremes: The Return of James Cameron” (The New Yorker). James Cameron is a beast worth studying. His track record is unparalleled, and few humans are as aggressive or as capable. Even if you’re feeling rushed, take 60 seconds to read the first paragraph of this piece, which is incredible. Kudos to Dana Goodyear (@danagoodyear) on the writing.— Tim Ferriss
“How 30 Days of Kindness Made Me a Better Person.” Click here for an easy-to-print image of the 30 acts of kindness.— Tim Ferriss
“Reality has a surprising amount of detail” by John Salvatier (@johnsalvatier). This 2017 beauty was sent to me by my dear friend, Pineapple-Eating Cat (long story). It made me recall my conversation with Tim O’Reilly and his daily habit of pausing to take a photograph of a flower. If you read this article, and it only takes 5–10 minutes, be sure to read to the end. Here are two teaser sections: This means it’s really easy to get stuck. Stuck in your current way of seeing and thinking about things. Frames are made out of the details that seem important to you. The important details you haven’t— Tim Ferriss
The French Burglar Who Pulled Off His Generation’s Biggest Art Heist (The New Yorker). After my previous mention of the Sour Grapes doc in 5BF, my brother, who’d also read Billionaire’s Vinegar, said, “Oh, if you like that, I have something you’ll really like.” He sent me this New Yorker piece. It blends theft and art in more ways than one.— Tim Ferriss
The Glorious, Almost-Disconnected Boredom of My Walk in Japan by Craig Mod (@craigmod). This remains one of my favorite pieces ever published by WIRED. I printed it out more than a year ago and reread it often, continuing to highlight new things. If you feel overwhelmed by the noise, or if you simply fantasize about being a stranger in a strange land, this is a wonderful transporter. Told through the lens of an ultra-marathon walk through Japan, Craig’s story contains a lot of gems, including paragraphs like these: I have configured servers, written code, built web pages, helped design product— Tim Ferriss
The Gift: Poems by Hafiz, the Great Sufi Master by Hafiz (translated by Daniel Ladinsky). Speaking as someone who actively avoided poetry for decades, I have a confession: Hafiz has become one of my favorite writers in the last year. I randomly (or not?) found this collection at a bookstore and flipped to several poems that made me burst out laughing, including “Two Giant Fat People.” Hafiz is a profound joker, and his poems are unlike any poetry I’ve ever seen. Here is part of the description from Amazon: “Chosen by author Elizabeth Gilbert as one of her ten favorite books, Daniel Ladinsky’s — Tim Ferriss
“All living things emit a faint glow. Could this light be useful?” by Jo Marchant (Nature). Here is one of the many wild paragraphs in this piece: Some experiments are harder to dismiss, says Cifra. A team led by biologist Rhys Mould at the University of Westminster, London, for example, studied isolated mitochondria in sealed quartz containers. Adding a toxin to one container decreased the respiration rate of mitochondria in adjacent ones, and mitochondria from cancer cells showed a stronger response than those from healthy cell lines did. The effect was blocked by an opaque barrier of alumin— Tim Ferriss
“Please Use AI” by Shawn Smucker. Don’t let the title fool you. It’s a beautiful reminder to remain human, despite pressures to mimic the machines we use. Hat tip to CS for the recommendation. This piece brings to mind a Kurt Vonnegut passage that is about telling his wife he’s going out to buy an envelope: “She says, ‘Well, you’re not a poor man. You know, why don’t you go online and buy a hundred envelopes and put them in the closet?’ And so I pretend not to hear her and go out to get an envelope, because I’m going to have a hell of a good time in the process of buying one envelope. I meet a— Tim Ferriss
“Inside the Secret Factory That Supplies Ukraine’s War Drones.” (Alternate link.) For a good pairing on the future of war-tech, watch “Palmer Luckey Wants America to Win.”— Tim Ferriss
“From Hierarchy to Intelligence” by Jack Dorsey and Roelof Botha. Here are a few excerpts to give you some idea of the gist: Block is remote-first. Everything we do creates artifacts. Decisions, discussions, code, designs, plans, problems, and progress all exist as recorded actions. It’s the raw material for a company world model. In a traditional company, a manager’s job is to know what’s happening across their team and relay that context up and down the chain. In a remote-first company where work is already machine-readable, AI can build and maintain that picture continuously. What’s being b— Tim Ferriss
“Better Than Free” by Kevin Kelly. Kevin (@kevin2kelly) is Senior Maverick at WIRED, which he co-founded in 1993, and he is the author of one of my favorite essays on making a living as a creator: “1,000 True Fans.” But if “1,000 True Fans” tells you who your customers might be, how do you figure out what to sell them, especially in the age of AI? I recently published “Has AI Already Killed How-To Nonfiction?,” and reader Andy Vaughn recommended another Kevin essay in the comments: “Better Than Free.” “Better Than Free” answers the what question, and I was shocked I hadn’t seen it before, as i— Tim Ferriss
“How do bilingual brains navigate between languages? Scientists discover ‘geometric neural map.’” This article describes new research just published in Cell, and it begins with the below paragraph: “Anyone who speaks more than one language knows the feeling of expressing the same thought through entirely different linguistic lenses. A new study by researchers at Rice University and Baylor College of Medicine reveals that the key to this translation ability is a shared geometric map of neural responses in the hippocampus.” It also discusses how neuroscience and AI may be converging on similar c— Tim Ferriss
“How to think in writing” by Henrik Karlsson.— Tim Ferriss
“I Solved My Mystery Fatigue with AI.”— Tim Ferriss
“Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?”— Tim Ferriss
“Has AI Already Killed How-To Nonfiction? Sales Trends, My Personal Data, and What It Might Mean for the Future.”— Tim Ferriss
“Curious cases of financial engineering in biotech.” This is an exceptional piece that felt like flipping a switch and suddenly seeing a broader spectrum of light. Hat tip to Phil Strandwitz of Holobiome for the recommendation. And congrats on the ARPA-H grant!— Tim Ferriss
"Gell-Mann amnesia effect" This was coined by the incredible author, Michael Crichton, who created Jurassic Park, the original Westworld ), the ER ) TV series, and countless others. From his Wikipedia page: [Crichton] explained that he had chosen the name ironically, because he had once discussed the effect with physicist Murray Gell-Mann, "and by dropping a famous name I imply greater importance to myself, and to the effect, than it would otherwise have." Briefly stated, the Gell-Mann Amnesia effect works as follows. You open the newspaper to an article on some subject you know well. In Murra— Tim Ferriss
“Your Feed Is Fake” (Vulture). (Alternate non-paywall link.) If you’re on social media, even as a casual browser, you should read this entire piece. It’ll give you 100 more reasons to delete your accounts and find better and safer hobbies. A few excerpts from the article: Joe Lim estimates that 90 percent of what you see on the internet is advertising in disguise, and he should know. For three years, Lim ran a company called Floodify, which at its peak operated 65,000 dummy social-media accounts used to drum up attention on behalf of paying clients. On a typical day, he says, Floodify posted 5— Tim Ferriss
“Riding the Leopard” by Packy McCormick.— Tim Ferriss
“The Greatest Investor You’ve Never Heard Of: An Optometrist Who Beat The Odds To Become A Billionaire” (Forbes, Alternate link). This is a wild read. There are some very smart lessons in here for those who read carefully. One benefit of the 2019 publication date is that you can now look up how his older investments (e.g., Heico) and newer bets at the time of its writing (e.g., GE) turned out. It’s practically the stuff of fantasy.— Tim Ferriss
“Getting closer to Her: From Moshi to Thinking Machines Interaction Model.” How do we actually get to the Scarlett Johansson companion in the movie Her? >From the above piece: “Real-time voice assistants [have been] small and dumb because anything bigger could not respond inside a human’s patience window. Frontier reasoning models [have been] astonishing in benchmark tables, but their real-time voice versions [feel lacking].” So what to do? Sure, you can try and cascade models together, but then you’re “adding latency, each handoff losing context, each silence between turns reminding you that — Tim Ferriss
“The Podcast Where You Can Eavesdrop on the A.I. Elite” by Benjamin Wallace (New York Times). (Alternate link.) From the subheading: “Dwarkesh Patel was a bored college sophomore looking for intellectual stimulation. Now he commands interviews with Jensen Huang and Mark Zuckerberg and holds his own with deeply nerdy A.I. researchers.” But how did Dwarkesh get started? Good old-fashioned chutzpah, combined with good writing: Mr. Patel recorded the first episode of “The Lunar Society,” his original name for the podcast, from his dorm room at the University of Texas at Austin in 2020, during the — Tim Ferriss
“Could At-Home Brain Stimulation Reduce Psychiatry’s Reliance on S.S.R.I.s?” by Rachel E. Gross (New York Times) (Alternate link.) “Top Psychiatrists Call for a Greater Focus on Ceasing Medication” by Ellen Barry (New York Times) (Alternate link.) One excerpt from the latter: “Various efforts within the psychopharmacology society aim to make deprescribing part of regular medical practice. One group is proposing the creation of a new insurance code so that doctors can be reimbursed for helping patients get off medications. Another is developing a clinical tool to help doctors ascertain whether — Tim Ferriss
“Some Contemporary Heresies” by Kevin Kelly. Having known Kevin a long time, I suspect that these are collected from some very smart people. Smart doesn’t always equal right, but it does add a little color to the wild statements. “Faith in the Possible.” This is the first article on Reid Hoffman’s new Substack Theory of the Game. This piece has a good fine-slicing of the religion of techno-optimism, which is reframed as creation. His description of the various religious factions is very good, and I hadn’t seen it put so succinctly before. One important footnote: read the comments. I’m sharing — Tim Ferriss
“Ocular Glymphatic System: Its Modulation and Role in Intraocular Tumors” by Dr. Jasmine H. Francis and Dr. David H. Abramson. The glymphatic system is worth getting familiar with. Excerpt: “The glymphatic system is a glial-based perivascular network that clears metabolic waste from the central nervous system (CNS), and its dysfunction is related to neurodegenerative disease.” New therapies for enhancing CNS glymphatic flow are discussed in this piece.— Tim Ferriss
“How to Keep Your Brain Sharp: A Practical Playbook Beyond the Basics” by Dr. Tommy Wood.— Tim Ferriss
“The New World: Joshua Kushner, Thrive Capital, and the American dream” by Jeremy Stern (Colossus).— Tim Ferriss
“Investigating Rapid-Acting TMS for Adolescent Depression.” Do you know a teenager (ages 13–20) experiencing symptoms of depression? If so, this may be worth a look. Dr. Sean O’Sullivan and his team at UT Austin are running a clinical trial using accelerated and personalized transcranial magnetic stimulation (TMS) to treat depression. It is drug-free, and the treatment is only five days long. This is the very approach I’ve used personally, and I had my most recent TMS treatment for GAD/OCD last week. The results are some of the most impressive I’ve ever seen. If you or someone you know might b— Tim Ferriss
“FBI Extracts Suspect’s Deleted Signal Messages Saved in iPhone Notification Database” (Alternate link). This is good to be aware of if you’re using encrypted communications for privacy.— Tim Ferriss
“How A.I. Helped One Man (and His Brother) Build a $1.8 Billion Company.” (The New York Times). From his house in Los Angeles, Mr. Gallagher, 41, used A.I. to write the code for the software that powers his company, produce the website copy, generate the images and videos for ads and handle customer service. He created A.I. systems to analyze his business’s performance. And he outsourced the other stuff he couldn’t do himself. His start-up, Medvi, a telehealth provider of GLP-1 weight-loss drugs, got 300 customers in its first month. In its second month, it gained 1,000 more. In 2025, Medvi’s — Tim Ferriss
“Tobacco plant altered to produce five psychedelic drugs” (New Scientist). Scientists at the Weizmann Institute genetically engineered a single tobacco plant to produce five psychedelic compounds—including psilocybin, DMT, and 5-MeO-DMT—using a technique that temporarily introduces genes from mushrooms, plants, and even the Colorado River toad. The approach could offer a simpler, more sustainable alternative to chemical synthesis for producing psychedelics for therapeutic research. For pairing and background, you can read my older article titled “An Urgent Plea to Users of Psychedelics: Let’s — Tim Ferriss
“Why Do Mind-Altering Drugs Make People Feel Better?” How do you break psychedelic molecules into parts, like cars in a chop shop, and build new ones? This is a thought-provoking New Yorker piece by Clayton Dalton, an ER doc and Ferriss-UC Berkeley Psychedelic Journalism Fellow. I like that this is a controversial piece. I hope it helps drive the science and conversation forward. On one hand, the “neuroplastogen” approach is often driven by business and financial incentives. If you can remove the hallucinations from psychedelics, your ability to fit within current medical structures (take-home— Tim Ferriss
“‘We have brothers, sons, lovers – but they can’t live here!’ The happy home shared by 26 women” by Anita Chaudhuri. “That this is an idea whose time has come, particularly for older people, is indisputable. In 2021, 3.64 million people aged over 65 were living alone in the UK, 70% of whom were women. In 10 years’ time, over-65s will have risen from 19% to an estimated 22% of the population, according to the latest report by the Centre for Ageing Better.”— Tim Ferriss
“My lobster lost $450,000 this weekend.” “Man accidentally gains control of 7,000 robot vacuums.” (Popular Science). (Original coverage: “The DJI Romo robovac had security so poor, this man remotely accessed thousands of them” for The Verge).— Tim Ferriss
Some of you might recall my mention of the potential liver toxicity risks of 1,3-butanediol-based ketone supplements 6–12 months ago. 1,3-butanediol—sometimes abbreviated as 1,3-BD, BDO, or 1,3-BDO—is found in the majority of the most popular ketone supplements. Even the monoester I’ve enjoyed refers to BHB bound to 1,3-BD. While I still occasionally consume it, I have strongly dialed back the dosages and frequency. I treat it more like a shot of moonshine and less like a nutritional supplement. A new study was just published February 19th that further supports exercising caution: “Disparate H— Tim Ferriss
“Going Founder Mode On Cancer.” After surgery, radiation, and brutal chemo failed to stop his cancer’s recurrence, co-founder of GitLab Sid Sijbrandij did what he knew best. In Silicon Valley’s parlance, he went “founder mode,” the term coined by Paul Graham to describe entrepreneurs who go deep and fully hands-on into a problem. Sid assembled a team, built a system of maximal diagnostics using cutting-edge, single-cell sequencing, and pursued 10+ experimental therapies in parallel, which included a radioligand treatment in Germany that most patients would never find. His cancer is now undetec— Tim Ferriss
“Baseball arbitration.” Pretty cool idea. A summary I found helpful: “Baseball arbitration” is named for its origin in Major League Baseball (MLB), where it was introduced in 1974 to resolve salary disputes for eligible players. It is called this because it specifically applies to the “final offer” format, where a panel must choose between the team’s salary offer and the player’s request. Key details about baseball arbitration: • Origin: Introduced in 1974 in the MLB to prevent holdouts. • Final Offer Mechanism: Unlike traditional arbitration, the panel cannot “split the baby” or create a comp— Tim Ferriss
“How I Beat Lyme Disease with The Ketogenic Diet.” I started writing this as a reply on X to Greg Yang, co-founder of xAI, who recently stepped down from xAI to address his debilitating case of Lyme disease. Ultimately, I decided that a blog post could provide more detail and allow proofreading by credible scientists, so here we are. The post covers the science, exact how-to protocols, and much more.— Tim Ferriss
“Alzheimer’s blood tests may be misleading for people with kidney problems.” Summary: “A large study found that people with impaired kidneys tend to have higher Alzheimer’s biomarkers, yet they don’t face a higher overall risk of dementia. For those who already have elevated biomarkers, kidney problems may speed up when symptoms appear. The findings show that kidney health can change how Alzheimer’s blood tests are read. Doctors may need to consider both organs to get a clearer picture.” Pair this article with my brand-new conversation with Dr. Tommy Wood on preventing dementia.— Tim Ferriss
“What is the question?” by Itai Yanai and Martin Lercher. This is an outstanding read. Even if you have little interest in how the best scientists work, this will help you become a better and more productive thinker. Take it from W. Edwards Deming, who is best known as the “father of the quality movement” for revolutionizing post-WWII Japan and making it one of the most dominant economies in the world: “If you do not know how to ask the right question, you discover nothing.”— Tim Ferriss
“The Plastic Inside Us” by Wynne Parry for UCSF Magazine. From the article: “Every day, in a thousand ways, we take advantage of the utility of plastic. It’s in our clothes, our cars, our cosmetics, and so much more. But eventually, these products turn into something else: tiny synthetic particles that spread quite literally everywhere—into our air, our food, our water, even inside of us. We are only beginning to tease out what the presence of these microplastics means for our health—and what we can do about it.” I hope to have more thoughts later this year about how to deal with PFAS “forever— Tim Ferriss
“Wall Street groups hire traders to wade into prediction markets” (FT; Alternate link). I’ve long been interested in prediction markets and the secondary and tertiary effects they’ll have on seemingly unrelated fields and bets.— Tim Ferriss
“The Technology Brothers Have Silicon Valley in Their Thrall. Now They’re Coming for You” by Julia Black (Vanity Fair). Do you think it’s too crowded to do X, whatever you might be considering? Well, think again, as there is always room if you aim to be the only and not simply the best. Owning a category of one, and being first mover, gives you a tremendous margin of safety. This is a fun read full of lessons. I suggest pairing it with this WSJ profile of the Acquired gents and how they carved out a spectacular niche (a big one!) in the saturated podcast ecosystem.— Tim Ferriss
“Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?” This will inform how I change my exercise moving forward, specifically related to increasing high-intensity interval training (HIIT). There are some wild insights and workout specifics coming soon to the podcast. Bookmark the last week of January, and you can subscribe to the podcast on Apple Podcasts, Spotify, or wherever else you get your fine audio morsels.— Tim Ferriss
“This is a weird comparison, but Zcash reminds me a lot of BitTorrent…” by Haseeb Qureshi. I think the nature of privacy, and how much we value it, will change fundamentally in the next 2–3 years, as the realities of being fully exposed become more obvious. For several years, I’ve been tracking privacy-reclaiming technologies, and this is one that I’m paying attention to. How would you like your online purchases, precise physical location, voting and dating preferences, health or health-adjacent information (e.g., wearables), and more to be correlated and made public? What if insurers and pote— Tim Ferriss
“Training the Idea Muscle: Riley Walz on creating viral internet pranks” by Aadil Pickle.— Tim Ferriss
“How Hungry Fat Cells Could Someday Starve Cancer to Death” (UCSF News). Here’s the punchline: “Scientists transformed energy-storing white fat cells into calorie-burning ‘beige’ fat. Once implanted, they outcompeted tumors for resources, beating back five different types of cancer in lab experiments.”— Tim Ferriss
“James Cameron On AI in Hollywood” by Trung Phan. There is a lot hiding in this piece, including some of the strategies that allowed Cameron to make The Terminator for ~$6.5M, thoughts on AI-first studios, and yet another clever move by the inimitable James Dyson. In the end links for the above, I also found a great interview from the always on-point Patrick O’Shaughnessy of Invest Like the Best: “Ari Emanuel’s ‘Anti-AI’ Bet on Live Entertainment.”— Tim Ferriss
“Multilingualism and Extending Healthspan.” From the article: “As the accompanying commentary asserted: ‘multilingual usage across the lifespan could be as important as campaigns that promote physical activity, or smoking cessation.’” Language learning can be one of the greatest joys of your life. It certainly has been for me, but it required letting go of all the high-school Spanish classes that had failed me. You just need better methods that are both fun and effective. Might be time to try out Duolingo and tackle that language that’s always been on your to-learn list! For more practical tip— Tim Ferriss
“The Quest to Reinvent Anesthesia” (UCSF Magazine). If successful, this could reshape healthcare and dramatically reduce costs. Description, bolding mine: “UCSF researchers are scouring millions of compounds – with help from tiny zebrafish – to create anesthetics safe enough to use without an anesthesiologist.”— Tim Ferriss